Hepatocellular cancer has been rising in the US due to the increase in Hepatitis B and C infections. Cirrhotic patients have a 3% a year risk of developing this. Symptoms include abdominal pain, fatigue, weight loss, or palpable mass, Diagnosis usually an ultrasound or CT with a biopsy. Alpha fetoprotein is elevated in 85%.
Treatment options include surgery, chemoembolization, transplant, radiofrequency ablation, radiation, cryosurgery, or chemotherapy. Chemotherapy agents include Sorafenib.