Esophageal cancer is the seventh most common cause of cancer death in the world. There are two histologies: adenocarcinomas and squamous cell cancers. Symptoms include dysphagia, weight loss, pain, hoarseness, and aspiration. Diagnosis includes an EGD and an endoscopic ultrasound. Staging includes imaging, such as CT and PET scans.
Treatment options include surgery, neoadjuvant chemotherapy and radiation, post operative chemoradiotherapy, or for metastatic disease chemotherapy alone. Chemotherapy agents include 5-FU, paclitaxel, docetaxel, vinorelbine, oxaliplatin, and irinotecan.